ISDIN Eryfotona Actinica SPF 50+ ($60)

“Sunscreen is always the most important product to pair with vitamin C, and this is one of my favorites. Sunscreen not only protects against skin cancer, but is also the most important anti-aging and photo-protective effect anyone can take in their daily skin-care routine. Sunscreen in combination with vitamin C can help brighten skin and prevent fine lines, wrinkles, spots, etc.” —Fort Lauderdale, FL dermatologist Dr. Matthew Elias

Paula’s Choice 10% Niacinamide Booster ($46)

“Niacinamide and vitamin C are both excellent ingredients for fighting off hyperpigmentation, so they’re great to use together. I like this formula because it can be mixed directly into your vitamin C serum.” —Toronto dermatologist Geeta Yadav, MD

skinbetter science Even Tone Correcting Serum ($150)

“Though it really depends on which vitamin C formula you are using, brightening products pair beautifully with vitamin C, as it already helps to even out our skin tone. You can boost that effect by using a brightening serum like this one. Vitamin C can also cause photosensitivity, so sunscreen is a non-negotiable when using it.” —Celebrity aesthetician Morgan Rackley

Alastin Skincare Restorative Skin Complex ($199)

“I recommend using a peptide serum twice a day, in conjunction with your vitamin C serum. This is an innovative peptide serum in a moisturizing base with TriHex Technology that boosts collagen and elastin synthesis and repair in the skin.” —Dr. Honet

EltaMD UV Clear Broad-Spectrum SPF 46 Sunscreen – Untinted 

“Vitamin C is a great product to pair with your daily sunscreen, in fact, they work in tandem to help keep skin optimally protected. Vitamin C is an antioxidant, so it helps scavenge any free radicals that your sunscreen might miss. While vitamin C isn’t a replacement for sunscreen by any means, it can help boost its efficacy when used together. This one from EltaMD is my favorite because it provides superb sun protection and won’t clog pores or irritate sensitive or acne-prone complexions. In fact, it actually improves acne with a unique combination of lactic acid and high-purity niacinamide.” —Dr. Schlessinger

Restorsea Restoring Night Cream ($185)

“I advise using vitamin C serum in the morning, and then a moisturizer with antioxidant ingredients and/or other actives at night. This hydrating moisturizer with Vibransea Complex—a proprietary salmon egg enzyme—gently and enzymatically exfoliates the skin. It also contains wild oat extract for anti-inflammatory benefits and honeysuckle extract for an antioxidative effect.” —Dr. Honet

Kiehl’s Ferulic Brew Antioxidant Treatment With Lactic Acid ($54)

“Ferulic acid is a potent antioxidant that helps stabilize vitamin C while strengthening its efficacy. This leave-on treatment can be used before your vitamin C serum to help support its results, and beyond ferulic acid, it contains lactic acid, a gentle AHA to help boost skin’s radiance, as well as nourishing squalane.” —Dr. Yadav

skinbetter science AlphaRet Overnight Cream ($130)

“Pairing vitamin C during the day with a retinoid at night can be very effective. This cream is an innovative combination of a retinoid and an alphahydroxy acid in an emollient, antioxidant base. It improves lines, wrinkles, texture, and uneven pigment, while reversing the signs of intrinsic and extrinsic aging and photodamage.” —Dr. Honet  

La Roche-Posay Toleriane Double Repair Face Moisturizer ($20)

“This is another nighttime moisturizer I recommend to patients who are using vitamin C serums. It provides gentle hydration and is well-tolerated by even the most sensitive skin. It contains ceramide-3, niacinamide, glycerin, and proprietary prebiotic thermal water, helping to repair the barrier of the skin and maintain effective hydration for up to 48 hours after application. It’s simple, effective and inexpensive.” —Dr. Honet